Semaglutide Dosage Guide: Your Complete Schedule
Proper dosing is key to maximizing semaglutide results while minimizing side effects. Here's the complete dosage guide for semaglutide weight loss therapy.
Standard Titration Schedule
- Weeks 1-4: 0.25mg weekly (adjustment phase)
- Weeks 5-8: 0.5mg weekly
- Weeks 9-12: 1.0mg weekly
- Weeks 13-16: 1.7mg weekly
- Week 17+: 2.4mg weekly (full therapeutic dose)
Why Gradual Dose Increases Matter
The gradual titration schedule isn't just a recommendation — it's essential. Starting at a low dose allows your body's GLP-1 receptors to adjust, dramatically reducing nausea and digestive side effects. Patients who rush to higher doses experience more side effects and are more likely to discontinue treatment.
Dose Adjustments
Your healthcare provider may modify the standard schedule based on your response. If side effects are significant at a new dose, you may stay at the current dose for an additional 4 weeks before increasing. Some patients achieve excellent results at 1.0mg or 1.7mg without needing the full 2.4mg dose.
Important Dosing Tips
- Inject on the same day each week (choose a day that's easy to remember)
- You can change your injection day if needed — just ensure at least 2 days between doses
- Semaglutide can be taken with or without food, at any time of day
- Never take a double dose to make up for a missed one
- Keep a dosing journal or set phone reminders
Learn how to properly inject semaglutide and find the best injection sites for comfortable administration.