Semaglutide Injection Sites: Where to Inject
Choosing the right injection site and rotating properly ensures comfortable, effective semaglutide treatment. Here's your complete guide to injection site selection.
1. Abdomen (Most Popular)
The abdomen is the preferred site for most patients. Inject at least 2 inches away from the belly button. Avoid the area directly around the navel and any scars. The large surface area makes rotation easy — alternate between left and right sides, upper and lower quadrants.
2. Front of Thighs
The front or outer middle third of the thigh is another excellent option. It's easy to see and access, making it a good choice for beginners. Alternate between left and right thighs weekly, and vary the exact spot within each thigh.
3. Back of Upper Arms
The back of the upper arm (triceps area) works well but may require assistance from another person. This site is preferred by some patients who experience more sensitivity in the abdomen or thighs.
Rotation Strategy
Use a simple rotation system:
- Week 1: Right side of abdomen
- Week 2: Left thigh
- Week 3: Left side of abdomen
- Week 4: Right thigh
- Repeat the cycle, varying the exact spot each time
Sites to Avoid
- Within 2 inches of the belly button
- Areas with scars, bruises, or skin irritation
- Hardened or lumpy areas from previous injections
- Areas with visible veins
For complete injection instructions, see our step-by-step injection guide and dosage guide.